Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the host cell plasma membrane. VP40 traffics to the pla...

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Bibliografiska uppgifter
I publikationen:Viruses
Huvudupphovsmän: Wijesinghe, Kaveesha J., McVeigh, Luke, Husby, Monica L., Bhattarai, Nisha, Ma, Jia, Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232359/
https://ncbi.nlm.nih.gov/pubmed/32344654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040482
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