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Tetrodotoxin, a Potential Drug for Neuropathic and Cancer Pain Relief?

Tetrodotoxin (TTX) is a potent neurotoxin found mainly in puffer fish and other marine and terrestrial animals. TTX blocks voltage-gated sodium channels (VGSCs) which are typically classified as TTX-sensitive or TTX-resistant channels. VGSCs play a key role in pain signaling and some TTX-sensitive V...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: González-Cano, Rafael, Ruiz-Cantero, M. Carmen, Santos-Caballero, Miriam, Gómez-Navas, Carlos, Tejada, Miguel Á., Nieto, Francisco R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310002/
https://ncbi.nlm.nih.gov/pubmed/34357955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13070483
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