Tetrodotoxin (TTX) as a Therapeutic Agent for Pain

Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions. TTX has been extensively used to functionally characterize VGSCs, which can be classified as TTX-sensitiv...

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Autors principals: Nieto, Francisco Rafael, Cobos, Enrique José, Tejada, Miguel Ángel, Sánchez-Fernández, Cristina, González-Cano, Rafael, Cendán, Cruz Miguel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296997/
https://ncbi.nlm.nih.gov/pubmed/22412801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10020281
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