Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia

Myelodysplastic Syndromes (MDSs) affect the elderly and can progress to Acute Myeloid Leukemia (AML). Epigenetic alterations including DNA methylation and chromatin modification may contribute to the initiation and progression of these malignancies. DNA hypomethylating agents such as decitabine and...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Pharmaceuticals (Basel)
Autori principali: Sorrentino, Vincent G., Thota, Srijan, Gonzalez, Edward A., Rameshwar, Pranela, Chang, Victor T., Etchegaray, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308509/
https://ncbi.nlm.nih.gov/pubmed/34358067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070641
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