Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia

Myelodysplastic Syndromes (MDSs) affect the elderly and can progress to Acute Myeloid Leukemia (AML). Epigenetic alterations including DNA methylation and chromatin modification may contribute to the initiation and progression of these malignancies. DNA hypomethylating agents such as decitabine and...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Sorrentino, Vincent G., Thota, Srijan, Gonzalez, Edward A., Rameshwar, Pranela, Chang, Victor T., Etchegaray, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308509/
https://ncbi.nlm.nih.gov/pubmed/34358067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070641
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