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Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes

Immune checkpoint inhibitors, as single-agent therapy, have shown modest clinical efficacy in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). As has been successfully shown in other less immunogenic hematologic malignancies, rationally designed combination approach...

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Bibliografski detalji
Izdano u:Leukemia
Glavni autori: Daver, Naval, Boddu, Prajwal, Garcia-Manero, Guillermo, Yadav, Shalini Singh, Sharma, Padmanee, Allison, James, Kantarjian, Hagop
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916728/
https://ncbi.nlm.nih.gov/pubmed/29487386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0070-8
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