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Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes

Immune checkpoint inhibitors, as single-agent therapy, have shown modest clinical efficacy in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). As has been successfully shown in other less immunogenic hematologic malignancies, rationally designed combination approach...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Daver, Naval, Boddu, Prajwal, Garcia-Manero, Guillermo, Yadav, Shalini Singh, Sharma, Padmanee, Allison, James, Kantarjian, Hagop
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916728/
https://ncbi.nlm.nih.gov/pubmed/29487386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0070-8
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