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Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes

Immune checkpoint inhibitors, as single-agent therapy, have shown modest clinical efficacy in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). As has been successfully shown in other less immunogenic hematologic malignancies, rationally designed combination approach...

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Podrobná bibliografie
Vydáno v:Leukemia
Hlavní autoři: Daver, Naval, Boddu, Prajwal, Garcia-Manero, Guillermo, Yadav, Shalini Singh, Sharma, Padmanee, Allison, James, Kantarjian, Hagop
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916728/
https://ncbi.nlm.nih.gov/pubmed/29487386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0070-8
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