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DNA Methylation and Intra-Clonal Heterogeneity: The Chronic Myeloid Leukemia Model
SIMPLE SUMMARY: In Chronic Myeloid Leukemia (CML), intra-clonal heterogeneity is a major factor in the response to tyrosine kinase inhibitors and in leukemia stem cell persistence. This intra-clonal heterogeneity could be partially explained by epigenetic abnormalities. This review focuses on DNA me...
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| Vydáno v: | Cancers (Basel) |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8307727/ https://ncbi.nlm.nih.gov/pubmed/34298798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143587 |
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