DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34(+) CD15(−) cells in early chronic‐phase chronic myeloid leukemia

Despite the high efficiency of tyrosine kinase inhibitors (TKI), some patients with chronic myeloid leukemia (CML) will display residual disease that can become resistant to treatment, indicating intraclonal heterogeneity in chronic‐phase CML (CP‐CML). To determine the basis of this heterogeneity, w...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Maupetit‐Mehouas, Stéphanie, Court, Franck, Bourgne, Céline, Guerci‐Bresler, Agnès, Cony‐Makhoul, Pascale, Johnson, Hyacinthe, Etienne, Gabriel, Rousselot, Philippe, Guyotat, Denis, Janel, Alexandre, Hermet, Eric, Saugues, Sandrine, Berger, Juliette, Arnaud, Philippe, Berger, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983208/
https://ncbi.nlm.nih.gov/pubmed/29575763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12191
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