DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34(+) CD15(−) cells in early chronic‐phase chronic myeloid leukemia

Despite the high efficiency of tyrosine kinase inhibitors (TKI), some patients with chronic myeloid leukemia (CML) will display residual disease that can become resistant to treatment, indicating intraclonal heterogeneity in chronic‐phase CML (CP‐CML). To determine the basis of this heterogeneity, w...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Maupetit‐Mehouas, Stéphanie, Court, Franck, Bourgne, Céline, Guerci‐Bresler, Agnès, Cony‐Makhoul, Pascale, Johnson, Hyacinthe, Etienne, Gabriel, Rousselot, Philippe, Guyotat, Denis, Janel, Alexandre, Hermet, Eric, Saugues, Sandrine, Berger, Juliette, Arnaud, Philippe, Berger, Marc G.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983208/
https://ncbi.nlm.nih.gov/pubmed/29575763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12191
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