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Elevated Levels of CTRP1 in Obesity Contribute to Tumor Progression in a p53-Dependent Manner

SIMPLE SUMMARY: Obesity is regarded as a risk factor for various cancers. However, the molecular mechanisms linking obesity with cancer remain primarily uncharacterized. In this study, we demonstrate that CTRP1, an adiponectin paralogue, promotes tumor growth in a p53-dependent manner. Obese mice on...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Park, Rackhyun, Jang, Minsu, Park, Yea-In, Park, Yeonjeong, Namkoong, Sim, Lee, Jin I., Park, Junsoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306638/
https://ncbi.nlm.nih.gov/pubmed/34298831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143619
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