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6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway

6-Azauridine (6-AZA), a pyrimidine nucleoside analogue, is known to exhibit both antitumor and antiviral activities. Although 6-AZA was discovered more than 60 years ago, the cellular effects of this compound are yet to be elucidated. Here, we report that 6-AZA regulates autophagy-mediated cell deat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cha, Yeo-Eun, Park, Rackhyun, Jang, Minsu, Park, Yea-In, Yamamoto, Ayane, Oh, Won Keun, Lee, Eun-Ju, Park, Junsoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000275/
https://ncbi.nlm.nih.gov/pubmed/33799444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062947
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