6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway

6-Azauridine (6-AZA), a pyrimidine nucleoside analogue, is known to exhibit both antitumor and antiviral activities. Although 6-AZA was discovered more than 60 years ago, the cellular effects of this compound are yet to be elucidated. Here, we report that 6-AZA regulates autophagy-mediated cell deat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cha, Yeo-Eun, Park, Rackhyun, Jang, Minsu, Park, Yea-In, Yamamoto, Ayane, Oh, Won Keun, Lee, Eun-Ju, Park, Junsoo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000275/
https://ncbi.nlm.nih.gov/pubmed/33799444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062947
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