2,2′-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy

Autophagy regulation is important for tumor cell survival. Activation and inhibition of autophagy can sensitize tumor cells to anticancer drugs. However, few autophagy-regulating small molecules are available to increase the efficacy of anticancer drugs. Here, we report that 2,2′-methylenebis (6-ter...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Jang, Minsu, Kim, Hyunju, Park, Rackhyun, Jo, Daum, Lee, Eun-Ju, Oh, Won Keun, Park, Junsoo
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777754/
https://ncbi.nlm.nih.gov/pubmed/29383142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22858
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