Sigma-1 Receptor Promotes Mitochondrial Bioenergetics by Orchestrating ER Ca(2+) Leak during Early ER Stress

The endoplasmic reticulum (ER) is a complex, multifunctional organelle of eukaryotic cells and responsible for the trafficking and processing of nearly 30% of all human proteins. Any disturbance to these processes can cause ER stress, which initiates an adaptive mechanism called unfolded protein res...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Koshenov, Zhanat, Oflaz, Furkan E., Hirtl, Martin, Pilic, Johannes, Bachkoenig, Olaf A., Gottschalk, Benjamin, Madreiter-Sokolowski, Corina T., Rost, Rene, Malli, Roland, Graier, Wolfgang F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305890/
https://ncbi.nlm.nih.gov/pubmed/34206832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070422
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