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Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2+)
Mitochondrial Ca(2+) uptake is a vital process that controls distinct cell and organelle functions. Mitochondrial calcium uptake 1 (MICU1) was identified as key regulator of the mitochondrial Ca(2+) uniporter (MCU) that together with the essential MCU regulator (EMRE) forms the mitochondrial Ca(2+)...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615007/ https://ncbi.nlm.nih.gov/pubmed/26489515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15602 |
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