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Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2+)

Mitochondrial Ca(2+) uptake is a vital process that controls distinct cell and organelle functions. Mitochondrial calcium uptake 1 (MICU1) was identified as key regulator of the mitochondrial Ca(2+) uniporter (MCU) that together with the essential MCU regulator (EMRE) forms the mitochondrial Ca(2+)...

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Publicat a:Sci Rep
Autors principals: Waldeck-Weiermair, Markus, Malli, Roland, Parichatikanond, Warisara, Gottschalk, Benjamin, Madreiter-Sokolowski, Corina T., Klec, Christiane, Rost, Rene, Graier, Wolfgang F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615007/
https://ncbi.nlm.nih.gov/pubmed/26489515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15602
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