Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells

Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD) and causes remodeling of the small airways. However, the exact smoke-induced effects on the different types of small airway epithelial cells (SAECs) are poorly understood. Here, using air–liquid interface (ALI) cultures,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wohnhaas, Christian T., Gindele, Julia A., Kiechle, Tobias, Shen, Yang, Leparc, Germán G., Stierstorfer, Birgit, Stahl, Heiko, Gantner, Florian, Viollet, Coralie, Schymeinsky, Jürgen, Baum, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305830/
https://ncbi.nlm.nih.gov/pubmed/34299265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147646
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