Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture

Cigarette smoke (CS) is the leading risk factor to develop COPD. Therefore, the pathologic effects of whole CS on the differentiation of primary small airway epithelial cells (SAEC) were investigated, using cells from three healthy donors and three COPD patients, cultured under ALI (air-liquid inter...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gindele, Julia A., Kiechle, Tobias, Benediktus, Kerstin, Birk, Gerald, Brendel, Michael, Heinemann, Fabian, Wohnhaas, Christian T., LeBlanc, Michelle, Zhang, Haijun, Strulovici-Barel, Yael, Crystal, Ronald G., Thomas, Matthew J., Stierstorfer, Birgit, Quast, Karsten, Schymeinsky, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148343/
https://ncbi.nlm.nih.gov/pubmed/32277131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63345-5
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