Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture

Cigarette smoke (CS) is the leading risk factor to develop COPD. Therefore, the pathologic effects of whole CS on the differentiation of primary small airway epithelial cells (SAEC) were investigated, using cells from three healthy donors and three COPD patients, cultured under ALI (air-liquid inter...

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Publicado no:Sci Rep
Main Authors: Gindele, Julia A., Kiechle, Tobias, Benediktus, Kerstin, Birk, Gerald, Brendel, Michael, Heinemann, Fabian, Wohnhaas, Christian T., LeBlanc, Michelle, Zhang, Haijun, Strulovici-Barel, Yael, Crystal, Ronald G., Thomas, Matthew J., Stierstorfer, Birgit, Quast, Karsten, Schymeinsky, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148343/
https://ncbi.nlm.nih.gov/pubmed/32277131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63345-5
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