Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids

A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine analogues. The compounds were evaluat...

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Publicado no:Molecules
Main Authors: Magoulas, George E., Afroudakis, Pantelis, Georgikopoulou, Kalliopi, Roussaki, Marina, Borsari, Chiara, Fotopoulou, Theano, Santarem, Nuno, Barrias, Emile, Tejera Nevado, Paloma, Hachenberg, Julia, Bifeld, Eugenia, Ellinger, Bernhard, Kuzikov, Maria, Fragiadaki, Irini, Scoulica, Effie, Clos, Joachim, Gul, Sheraz, Costi, Maria Paola, de Souza, Wanderley, Prousis, Kyriakos C., Cordeiro da Silva, Anabela, Calogeropoulou, Theodora
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305768/
https://ncbi.nlm.nih.gov/pubmed/34299479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144204
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