Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids

A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine analogues. The compounds were evaluat...

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Vydáno v:Molecules
Hlavní autoři: Magoulas, George E., Afroudakis, Pantelis, Georgikopoulou, Kalliopi, Roussaki, Marina, Borsari, Chiara, Fotopoulou, Theano, Santarem, Nuno, Barrias, Emile, Tejera Nevado, Paloma, Hachenberg, Julia, Bifeld, Eugenia, Ellinger, Bernhard, Kuzikov, Maria, Fragiadaki, Irini, Scoulica, Effie, Clos, Joachim, Gul, Sheraz, Costi, Maria Paola, de Souza, Wanderley, Prousis, Kyriakos C., Cordeiro da Silva, Anabela, Calogeropoulou, Theodora
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305768/
https://ncbi.nlm.nih.gov/pubmed/34299479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144204
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