Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids

A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine analogues. The compounds were evaluat...

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Publicat a:Molecules
Autors principals: Magoulas, George E., Afroudakis, Pantelis, Georgikopoulou, Kalliopi, Roussaki, Marina, Borsari, Chiara, Fotopoulou, Theano, Santarem, Nuno, Barrias, Emile, Tejera Nevado, Paloma, Hachenberg, Julia, Bifeld, Eugenia, Ellinger, Bernhard, Kuzikov, Maria, Fragiadaki, Irini, Scoulica, Effie, Clos, Joachim, Gul, Sheraz, Costi, Maria Paola, de Souza, Wanderley, Prousis, Kyriakos C., Cordeiro da Silva, Anabela, Calogeropoulou, Theodora
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305768/
https://ncbi.nlm.nih.gov/pubmed/34299479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144204
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