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Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia

SIMPLE SUMMARY: Many patients are still dying from acute myeloid leukemia (AML). Initial treatment of this blood-borne cancer consists of chemotherapy, usually with the agent cytarabine (AraC). However, the cancer cells can become drug resistant and unresponsive to AraC, which complicates further tr...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Schönthal, Axel H., Swenson, Steve, Minea, Radu O., Kim, Hye Na, Cho, Heeyeon, Mohseni, Nazleen, Kim, Yong-Mi, Chen, Thomas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305595/
https://ncbi.nlm.nih.gov/pubmed/34298603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143385
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