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CXCL12-CXCR4/CXCR7 Axis in Colorectal Cancer: Therapeutic Target in Preclinical and Clinical Studies

Chemokines are chemotactic cytokines that promote cancer growth, metastasis, and regulate resistance to chemotherapy. Stromal cell-derived factor 1 (SDF1) also known as C-X-C motif chemokine 12 (CXCL12), a prognostic factor, is an extracellular homeostatic chemokine that is the natural ligand for ch...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Khare, Tripti, Bissonnette, Marc, Khare, Sharad
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305488/
https://ncbi.nlm.nih.gov/pubmed/34298991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147371
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