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Targeting CXCL12/CXCR4 Axis in Tumor Immunotherapy

Chemokines, which have chemotactic abilities, are comprised of a family of small cytokines with 8–10 kilodaltons. Chemokines work in immune cells by trafficking and regulating cell proliferation, migration, activation, differentiation, and homing. CXCR-4 is an alpha-chemokine receptor specific for s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Med Chem
Hauptverfasser: Zhou, Weiqiang, Guo, Shanchun, Liu, Mingli, Burow, Matthew E., Wang, Guangdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949083/
https://ncbi.nlm.nih.gov/pubmed/28875842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867324666170830111531
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