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Targeting the CXCR4/CXCL12 axis with the peptide antagonist E5 to inhibit breast tumor progression
Emerging evidence has demonstrated that stromal cell-derived factor 1 (SDF-1) and its cognate receptor CXCR4 have critical roles in tumorigenesis, angiogenesis and metastasis. In this study, we demonstrated the significant inhibitory effects of a novel chemically synthetic peptide (E5) on the CXCR4/...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Signal Transduct Target Ther |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661635/ https://ncbi.nlm.nih.gov/pubmed/29263923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.33 |
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