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PXR Modulates the Prostate Cancer Cell Response to Afatinib by Regulating the Expression of the Monocarboxylate Transporter SLC16A1

SIMPLE SUMMARY: Many kinase inhibitors have been tested as potential alternatives for the treatment of castration-resistant prostate cancers. However, none of these clinical trials led to drug approval despite interesting responses. Our study reveals that genes involved in drug metabolism and their...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Matheux, Alice, Gassiot, Matthieu, Fromont, Gaëlle, Leenhardt, Fanny, Boulahtouf, Abdelhay, Fabbrizio, Eric, Marchive, Candice, Garcin, Aurélie, Agherbi, Hanane, Combès, Eve, Evrard, Alexandre, Houédé, Nadine, Balaguer, Patrick, Gongora, Céline, Mbatchi, Litaty C., Pourquier, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305337/
https://ncbi.nlm.nih.gov/pubmed/34298852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143635
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