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The novel antibacterial compound walrycin A induces human PXR transcriptional activity
The human pregnane X receptor (PXR) is a ligand-regulated transcription factor belonging to the nuclear receptor superfamily. PXR is activated by a large, structurally diverse, set of endogenous and xenobiotic compounds, and coordinates the expression of genes central to metabolism and excretion of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435511/ https://ncbi.nlm.nih.gov/pubmed/22314385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs073 |
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