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Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments

The study of the platelet receptor integrin αIIbβ3 in a membrane-mimetic environment without interfering signalling pathways is crucial to understand protein structure and dynamics. Our understanding of this receptor and its sequential activation steps has been tremendously progressing using structu...

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Detalhes bibliográficos
Publicado no:Membranes (Basel)
Main Authors: Janke, Una, Mitlehner, Alexandra, Weide, Aileen, Gutmann, Theresia, Delcea, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304682/
https://ncbi.nlm.nih.gov/pubmed/34209233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes11070499
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