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Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes
Integrins are transmembrane proteins involved in hemostasis, wound healing, immunity and cancer. In response to intracellular signals and ligand binding, integrins adopt different conformations: the bent (resting) form; the intermediate extended form; and the ligand-occupied active form. An integrin...
Gorde:
| Argitaratua izan da: | PLoS One |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461286/ https://ncbi.nlm.nih.gov/pubmed/30978226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214969 |
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