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Biopolymer-coated gold nanoparticles inhibit human insulin amyloid fibrillation

Deposits of protein misfolding and/or aggregates are a pathological hallmark of amyloid-related diseases. For instance, insulin amyloid fibril deposits have been observed in patients with insulin-dependent diabetes mellitus after insulin administration. Here, we report on the use of AuNPs functional...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meesaragandla, Brahmaiah, Karanth, Sanjai, Janke, Una, Delcea, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217893/
https://ncbi.nlm.nih.gov/pubmed/32398693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64010-7
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