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Synonymous Codon Pair Recoding of the HIV-1 env Gene Affects Virus Replication Capacity
Synonymous codon pair deoptimization is an efficient strategy for virus attenuation; however, the underlying mechanism remains controversial. Here, we optimized and deoptimized the codon pair bias (CPB) of the human immunodeficiency virus type 1 (HIV-1) envelope (env) gene to investigate the influen...
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| Veröffentlicht in: | Cells |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8304268/ https://ncbi.nlm.nih.gov/pubmed/34209946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071636 |
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