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HIV-1 Protease Evolvability Is Affected by Synonymous Nucleotide Recoding
One unexplored aspect of HIV-1 genetic architecture is how codon choice influences population diversity and evolvability. Here we compared the levels of development of HIV-1 resistance to protease inhibitors (PIs) between wild-type (WT) virus and a synthetic virus (MAX) carrying a codon-pair-reengin...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6069183/ https://ncbi.nlm.nih.gov/pubmed/29875244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00777-18 |
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