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Synonymous genome recoding: a tool to explore microbial biology and new therapeutic strategies

Synthetic genome recoding is a new means of generating designed organisms with altered phenotypes. Synonymous mutations introduced into the protein coding region tolerate modifications in DNA or mRNA without modifying the encoded proteins. Synonymous genome-wide recoding has allowed the synthetic ge...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Martínez, Miguel Angel, Jordan-Paiz, Ana, Franco, Sandra, Nevot, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846928/
https://ncbi.nlm.nih.gov/pubmed/31584076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz831
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