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A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1

Ubiquitin fold modifier 1 (UFM1) is a member of the ubiquitin-like protein family. UFM1 undergoes a cascade of enzymatic reactions including activation by UBA5 (E1), transfer to UFC1 (E2) and selective conjugation to a number of target proteins via UFL1 (E3) enzymes. Despite the importance of ufmyla...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Wesch, Nicole, Löhr, Frank, Rogova, Natalia, Dötsch, Volker, Rogov, Vladimir V.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304084/
https://ncbi.nlm.nih.gov/pubmed/34299007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147390
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