An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5

Short linear motifs, known as LC3-interacting regions (LIRs), interact with mactoautophagy/autophagy modifiers (Atg8/LC3/GABARAP proteins) via a conserved universal mechanism. Typically, this includes the occupancy of 2 hydrophobic pockets on the surface of Atg8-family proteins by 2 specific aromati...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Huber, Jessica, Obata, Miki, Gruber, Jens, Akutsu, Masato, Löhr, Frank, Rogova, Natalia, Güntert, Peter, Dikic, Ivan, Kirkin, Vladimir, Komatsu, Masaaki, Dötsch, Volker, Rogov, Vladimir V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984602/
https://ncbi.nlm.nih.gov/pubmed/30990354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1606637
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