Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation

The covalent conjugation of ubiquitin-fold modifier 1 (UFM1) to proteins generates a signal that regulates transcription, response to cell stress, and differentiation. Ufmylation is initiated by ubiquitin-like modifier activating enzyme 5 (UBA5), which activates and transfers UFM1 to ubiquitin-fold...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Habisov, Sabrina, Huber, Jessica, Ichimura, Yoshinobu, Akutsu, Masato, Rogova, Natalia, Loehr, Frank, McEwan, David G., Johansen, Terje, Dikic, Ivan, Doetsch, Volker, Komatsu, Masaaki, Rogov, Vladimir V., Kirkin, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861472/
https://ncbi.nlm.nih.gov/pubmed/26929408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715474
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