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Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding

Deubiquitinases (DUBs) are vital for the regulation of ubiquitin signals, and both catalytic activity of and target recruitment by DUBs need to be tightly controlled. Here, we identify asparagine hydroxylation as a novel posttranslational modification involved in the regulation of Cezanne (also know...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mader, Julia, Huber, Jessica, Bonn, Florian, Dötsch, Volker, Rogov, Vladimir V., Bremm, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039550/
https://ncbi.nlm.nih.gov/pubmed/31937588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010315
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