Silencing of HMGA2 by siRNA Loaded Methotrexate Functionalized Polyamidoamine Dendrimer for Human Breast Cancer Cell Therapy

The transcription factor high mobility group protein A2 (HMGA2) plays an important role in the pathogenesis of some cancers including breast cancer. Polyamidoamine dendrimer generation 4 is a kind of highly branched polymeric nanoparticle with surface charge and highest density peripheral groups tha...

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Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Abedi Gaballu, Fereydoon, Cho, William Chi-Shing, Dehghan, Gholamreza, Zarebkohan, Amir, Baradaran, Behzad, Mansoori, Behzad, Abbaspour-Ravasjani, Soheil, Mohammadi, Ali, Sheibani, Nader, Aghanejad, Ayuob, Ezzati Nazhad Dolatabadi, Jafar
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303903/
https://ncbi.nlm.nih.gov/pubmed/34356120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071102
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