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Silencing of HMGA2 by siRNA Loaded Methotrexate Functionalized Polyamidoamine Dendrimer for Human Breast Cancer Cell Therapy

The transcription factor high mobility group protein A2 (HMGA2) plays an important role in the pathogenesis of some cancers including breast cancer. Polyamidoamine dendrimer generation 4 is a kind of highly branched polymeric nanoparticle with surface charge and highest density peripheral groups tha...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Abedi Gaballu, Fereydoon, Cho, William Chi-Shing, Dehghan, Gholamreza, Zarebkohan, Amir, Baradaran, Behzad, Mansoori, Behzad, Abbaspour-Ravasjani, Soheil, Mohammadi, Ali, Sheibani, Nader, Aghanejad, Ayuob, Ezzati Nazhad Dolatabadi, Jafar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303903/
https://ncbi.nlm.nih.gov/pubmed/34356120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071102
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