Anti-Inflammatory Effect of Very High Dose Local Vessel Wall Statin Administration: Poly(L,L-Lactide) Biodegradable Microspheres with Simvastatin for Drug Delivery System (DDS)

Atherosclerosis involves an ongoing inflammatory response of the vascular endothelium and vessel wall of the aorta and vein. The pleiotropic effects of statins have been well described in many in vitro and in vivo studies, but these effects are difficult to achieve in clinical practice due to the lo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wacinski, Piotr, Gadzinowski, Mariusz, Dabrowski, Wojciech, Szumilo, Justyna, Wacinski, Jakub, Oru, Nathalie, Vicaut, Eric, Czuczwar, Stanislaw, Kocki, Janusz, Basinska, Teresa, Slomkowski, Stanislaw
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303821/
https://ncbi.nlm.nih.gov/pubmed/34299106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147486
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