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Anti-Inflammatory Effect of Very High Dose Local Vessel Wall Statin Administration: Poly(L,L-Lactide) Biodegradable Microspheres with Simvastatin for Drug Delivery System (DDS)

Atherosclerosis involves an ongoing inflammatory response of the vascular endothelium and vessel wall of the aorta and vein. The pleiotropic effects of statins have been well described in many in vitro and in vivo studies, but these effects are difficult to achieve in clinical practice due to the lo...

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Publicat a:Int J Mol Sci
Autors principals: Wacinski, Piotr, Gadzinowski, Mariusz, Dabrowski, Wojciech, Szumilo, Justyna, Wacinski, Jakub, Oru, Nathalie, Vicaut, Eric, Czuczwar, Stanislaw, Kocki, Janusz, Basinska, Teresa, Slomkowski, Stanislaw
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303821/
https://ncbi.nlm.nih.gov/pubmed/34299106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147486
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