Cargando...
Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor
More than 80% of colorectal cancer patients have adenomatous polyposis coli (APC) mutations, which induce abnormal WNT/β-catenin activation. Tankyrase (TNKS) mediates the release of active β-catenin, which occurs regardless of the ligand that translocates into the nucleus by AXIN degradation via the...
Guardado en:
| Publicado en: | Int J Mol Sci |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8303674/ https://ncbi.nlm.nih.gov/pubmed/34298950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147330 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|