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Inhibition of the Combinatorial Signaling of Transforming Growth Factor-Beta and NOTCH Promotes Myotube Formation of Human Pluripotent Stem Cell-Derived Skeletal Muscle Progenitor Cells

Understanding the signaling pathways that regulate the final differentiation of human myoblasts is essential for successful cell transplantation and drug screening for the treatment of muscular dystrophy. In an effort to improve myotube formation from hiPSC-derived myoblasts, we validated a collecti...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Choi, In Young, Lim, Ho Tae, Che, Young Hyun, Lee, Gabsang, Kim, Yong Jun
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303216/
https://ncbi.nlm.nih.gov/pubmed/34209364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071649
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