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Inhibition of the Combinatorial Signaling of Transforming Growth Factor-Beta and NOTCH Promotes Myotube Formation of Human Pluripotent Stem Cell-Derived Skeletal Muscle Progenitor Cells

Understanding the signaling pathways that regulate the final differentiation of human myoblasts is essential for successful cell transplantation and drug screening for the treatment of muscular dystrophy. In an effort to improve myotube formation from hiPSC-derived myoblasts, we validated a collecti...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Choi, In Young, Lim, Ho Tae, Che, Young Hyun, Lee, Gabsang, Kim, Yong Jun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303216/
https://ncbi.nlm.nih.gov/pubmed/34209364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071649
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