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Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine

Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all vertebrate classes. In mammals, bile salt composition is determined by host and microbial enzymes, affecting signaling through the bile salt–binding transcription factor farnesoid X receptor (Fxr). How...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wen, Jia, Mercado, Gilberto Padilla, Volland, Alyssa, Doden, Heidi L., Lickwar, Colin R., Crooks, Taylor, Kakiyama, Genta, Kelly, Cecelia, Cocchiaro, Jordan L., Ridlon, Jason M., Rawls, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302129/
https://ncbi.nlm.nih.gov/pubmed/34301599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg1371
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