Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine

Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all vertebrate classes. In mammals, bile salt composition is determined by host and microbial enzymes, affecting signaling through the bile salt–binding transcription factor farnesoid X receptor (Fxr). How...

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Vydáno v:Sci Adv
Hlavní autoři: Wen, Jia, Mercado, Gilberto Padilla, Volland, Alyssa, Doden, Heidi L., Lickwar, Colin R., Crooks, Taylor, Kakiyama, Genta, Kelly, Cecelia, Cocchiaro, Jordan L., Ridlon, Jason M., Rawls, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302129/
https://ncbi.nlm.nih.gov/pubmed/34301599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg1371
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