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α-Synuclein Strains: Does Amyloid Conformation Explain the Heterogeneity of Synucleinopathies?

Synucleinopathies are a heterogeneous group of neurodegenerative diseases with amyloid deposits that contain the α-synuclein (SNCA/α-Syn) protein as a common hallmark. It is astonishing that aggregates of a single protein are able to give rise to a whole range of different disease manifestations. Th...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Hoppe, Simon Oliver, Uzunoğlu, Gamze, Nussbaum-Krammer, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301881/
https://ncbi.nlm.nih.gov/pubmed/34201558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11070931
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