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Can Glycosylation Mask the Detection of MHC Expressing p53 Peptides by T Cell Receptors?

Proteins of the major histocompatibility complex (MHC) class I, or human leukocyte antigen (HLA) in humans interact with endogenous peptides and present them to T cell receptors (TCR), which in turn tune the immune system to recognize and discriminate between self and foreign (non-self) peptides. Of...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Nguyen, Thanh Binh, Lane, David P., Verma, Chandra S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301869/
https://ncbi.nlm.nih.gov/pubmed/34356680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071056
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