Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays

In the search for new therapeutic strategies to contrast SARS-CoV-2, we here studied the interaction of polydatin (PD) and resveratrol (RESV)—two natural stilbene polyphenols with manifold, well known biological activities—with Spike, the viral protein essential for virus entry into host cells, and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomolecules
Prif Awduron: Perrella, Fulvio, Coppola, Federico, Petrone, Alessio, Platella, Chiara, Montesarchio, Daniela, Stringaro, Annarita, Ravagnan, Giampietro, Fuggetta, Maria Pia, Rega, Nadia, Musumeci, Domenica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301781/
https://ncbi.nlm.nih.gov/pubmed/34356672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071048
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