Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays

In the search for new therapeutic strategies to contrast SARS-CoV-2, we here studied the interaction of polydatin (PD) and resveratrol (RESV)—two natural stilbene polyphenols with manifold, well known biological activities—with Spike, the viral protein essential for virus entry into host cells, and...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Perrella, Fulvio, Coppola, Federico, Petrone, Alessio, Platella, Chiara, Montesarchio, Daniela, Stringaro, Annarita, Ravagnan, Giampietro, Fuggetta, Maria Pia, Rega, Nadia, Musumeci, Domenica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301781/
https://ncbi.nlm.nih.gov/pubmed/34356672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071048
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